Nnpurpura de schonlein henoch pdf

The characteristic pathological feature of this vasculitis is iga immune complex deposition in vascular walls of the affected organs. Henoch schonlein purpura hsp is an immune mediated disease associated immunoglobulin a iga deposition within the affected organs. It is characterized by palpable purpura, arthritis, abdominal. Please use one of the following formats to cite this article in your essay, paper or report. In 1990 the american college of rheumatology acr proposed classification criteria for patients with vasculitides1, 5 by analysing 807 adults patients with different form of vasculitis. It is characterized by palpable purpura, arthralgia arthritis, abdominal and renal involvement.

While the disease is commonly seen in the pediatric age group. William heberden, a london physician, described the first cases of henoch schonlein purpura hsp in in describing hsp, heberden wrote of a. Gastroenterology research practice 2010, article id 597648. The disease is characterized by abnormal deposits of immunoglobulin a an antibody in the blood vessels, leading to their inflammation vasculitis. Its etiology remains unknown, but various stimuli have been proposed to trigger this pathology, namely infectious agents, drugs and tumor antigens. In the skin, the disease causes palpable purpura small, raised areas of bleeding underneath the skin, often with joint pain and abdominal pain. Ten years of experience at a moderate risk office of a general hospital a. With kidney involvement, there may be a loss of small amounts of blood and. Henoch schonlein purpura hsp is the most common form of acute vasculitis primarily affecting children. Clinical features include skin rashes, arthritis, abdominal pain and nephritis. This disease is mainly characterized by palpable purpura, arthritis arthralgia, abdominal pain, and kidney. Henoch schonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels. Henoch schonlein purpura hsp affects the blood vessels and causes a spotty rash. Hsp is the leading type of systemic vasculitis in the world.